Dehydroepiandrosterone (DHEA) is the most abundant corticosteroid hormone in the body, and it acts as a substrate for a variety of other hormones. Current research demonstrates that DHEA levels steadily decline with age after approximately age 25, reaching a low at age 80 of only about 5% of that of a 20-year-old. DHEA converts to (or stimulates the production of) estrogen, testosterone, cortisone and many other steroid ­hormones as needed by the body. ­Additionally, some cells have specific DHEA receptor sites. Research suggests that DHEA supports the maintenance of normal adrenal and immune function, bone density, healthy skin, and sexual health. Karuna’s DHEA contains biochemically pure DHEA in amounts suitable for flexible dosing. We do not use wild yam or other sources claiming to contain “natural” DHEA precursors, because studies demonstrate these precursors cannot be activated in the human body.

• DHEA is an adrenocortical hormone, the most abundant steroid hormone in the body, which acts as a substrate in the synthesis of a variety of other vital hormones (Lancet 1994;343: 1479-81; Gyncecol Endocrinol 1999; 13:15-25)..
• It is understood that levels of DHEA decrease steadily as the body ages and as a result of declining health (Proc Natl Acad Sci U S A 2000;97:4279-84; Ann NY Acad Sci 1995;774:128-42; Altern Med Rev 1996;1:60-9).
• Double-blind trials have reported increases in perceived physical and psychological well-being with DHEA supplementation (J Clin Encocrinol Metab 1994;78:1360; Am J Psychiatry 1999;156:646-9).
• Controlled research demonstrates that DHEA supplementation increases epidermal thickness, sebum production, skin hydration, and decreases facial skin pigmentation in the elderly (Proc Natl Acad Sci U S A 2000;97:4279-84).
• Improved immune responses have also been reported after DHEA supplementation (J Gerontol A Biol Sci Med Sci 1997;52:M1-7; Am J Obstet Gynecol 1993;169:1536-9).
• Taking DHEA helps support normal functioning of the adrenal glands (J Clin Endocrinol Metab 2002;87:2046-52; N Engl J Med 1999;341:1013-20).
• Improved sexual function in men was reported in a double-blind trial of DHEA (Urology 1999;53:590-5).
• Taking DHEA supports healthy bone density in men and women (Chin Med J (Engl) 2002;115:402-4; Clin Endocrinol (Oxf) 2000;53:561-8)..
• Wild yam and other sources claiming DHEA activity are not effective for raising DHEA levels in the human body (JAMA 1996;276:1365-7; Life
  Sci 1996;59:PL147-57)..

Other ingredients: vegetarian capsule, microcrystalline cellulose

Suggested use for adults:

• One capsule daily, as directed.

Caution: This product should not be taken without professional supervision, especially by patients with a personal or family history of hormone-related conditions, heart disease, mood disorders, or liver dysfunction.

For more information feel free to review Natural Hormones for Men:

This is an extensive library of useful articles and information. The original and thought-provoking work by John R. Lee, M.D. about men's hormones, how men can use natural hormones for optimal health, causes of prostate cancer and more. Men have hormone imbalances that can cause fatigue, weight gain, foggy thinking, irritability, prostate problems and loss of sex drive. Find out if you or a man in your life might be suffering from andropause. What it means when testosterone, DHEA and growth hormone are low or high in men. How testing hormones can help achieve male hormone balance. Why each recommended hormone is relevant to hormone balance for men. And more...