Proper digestion requires both a gastric phase supplying hydrochloric acid and pepsin, and an alkaline duodenal phase supplying protease, amylase, and lipase enzymes. DuoZyme provides all of these factors in a single, convenient, high potency capsule delivery system.

DuoZyme utilizes the technologically superior enzyme-release system which was favorably evalutated by Dr. David Graham in An Enteric-Coated Pancreatic Enzyme Preparation That Works (Dig Dis Sci 1979;24:906-9).

Refer to About...Bile Salts, Hydrochloric Acid and Pancreatic Enzymes as listed at the top of this page.
DuoZyme contains the acidulants betaine HCl and glutamic HCl, which help acidify gastric contents, creating a favorable environment for the proteolytic action of pepsin.
Pancreatin and ox bile extract, contained in pH-sensitive microspheres, supplement the natural secretions of the pancreas and liver, and promote the intestinal phase of digestion.
pH-sensitive microspheres typically provide a more effective means for delivering intact enzymes to the small intestine to reduce malabsorption of macronutrients (Dig Dis Sci 1979; 24:906-9).
Supplement Facts
Serving Size - 2 capsules
Servings per container 45 or 90
Amount per serving: %DV
Gastric Phase:
Betaine HCl (gastric phase) 300 mg â€
Glutamic HCl (gastric phase) 300 mg â€
Papain (enzyme blend) (gastric phase) 100 mg â€
Pepsin (enzyme blend) (1:15,000)*
(Equal to 100 mg of 1:3,000 strength pepsin) (gastric phase) 40 mg â€
Duodenal Phase:
Pancreatin (6x conc.)*
(duodenal phase) 300 mg â€
Ox Bile Extract* (duodenal phase) 120 mg â€
† Daily Value (DV) not established

* from FDA approved BSE-free freeze-dried source

Other ingredients: capsule (gelatin), silica, stearic acid (vegetable source), magnesium stearate (vegetable source), maltodextrin

Each serving provides at least the following:

Protease 45,000 USP Units
Amylase 45,000 USP Units
Lipase 7,500 USP Units
Suggested use for adults:

Two or more capsules, taken with meals, or as directed.
Warning: Patients with active peptic ulcer should use HCl products with caution.